Zopiclone, also sold under the brand name Imovane, is a non-benzodiazepine hypnotic sleeping medication that has demonstrated proven safety and efficacy in the treatment of insomnia. A clinical review took place to compare the effects of this medication to several benzodiazepines in the treatment of insomnia. It found that Imovane 7.5 mg produced efficacy equivalent to these medications except with less daytime sedation.
The clinical review also found that withdrawal symptoms and rebound insomnia are uncommon among Imovane-treated patients upon discontinuation of treatment. In general, other benefits of zopiclone include:
Imovane has a fast onset of effect and is typically effective for relieving the symptoms of insomnia on the first night of treatment. This medication is effective at treating sleep onset insomnia which refers to difficulty falling asleep after the lights have been switched off. People with sleep onset insomnia often take longer than 20-30 minutes to fall asleep. Imovane can, however, significantly reduce the amount of time it takes to transition from wakefulness to sleep.
Benefits of zopiclone also include the treatment of middle-of-the-night (MOTN) insomnia. Also known as sleep maintenance insomnia, MOTN insomnia is characterised by frequent nocturnal awakenings. It is not unusual for a patient with this condition to spend at least 20-30 minutes struggling to get back to sleep. This usually leads to excessive daytime sleepiness so using Imovane to prevent nighttime awakenings can beneficial at improving overall sleep quality and quantity.
Weight loss is a potential side effect of Zimovane / Imovane and some people add it under secondary benefits of zopiclone 7.5 mg. A possible reason for this is that insomnia and a lack of sleep have been linked to weight gain and obesity. Clinical studies have revealed that insufficient sleep tends to increase levels of a hormone in the body called ghrelin. Ghrelin is also known as the "hunger hormone" and it generally enhances appetite which leads to increased food intake.
Leptin, on the other hand, is a hormone that suppresses the appetite and this tends to decrease with a lack of sleep. A clinical study found that short habitual sleep durations led to increased body mass index (BMI) due to increased ghrelin and reduced leptin. Altogether, 1,024 volunteers were involved in the study and the researchers found that an average sleep duration of less than 7.7 hours each night was associated with an increased BMI.
Insomnia is often caused by medical conditions like arthritis as well as poor sleep habits like consuming caffeine in the evening. However, about 50 percent of people with insomnia report having the condition due to stress or anxiety. Worries about responsibilities and obligations as well as the day's events are common thoughts that provoke anxiety and prevent sleep. Anxiety prevents sleep as it can put your system into a "fight or flight" mode, contemplating all possible outcomes for whatever is worrying you.
Anxiety often leads to sleep disturbances like regular awakenings during the night. Waking up often reduces sleep quality, particularly if takes a long time to get back to sleep. Many people get stressed about not getting enough sleep to be able to function during the day, making sleep even more difficult to achieve. Therefore, insomnia and anxiety are two conditions that have a bidirectional relationship whereby the one condition can make the other worse.
A study took place to assess the hypnotic and anti-anxiety benefits of zopiclone 7.5 mg tablets / Imovane compared with a sleeping pill called nitrazepam in the treatment of insomnia. In total, 20 patients with insomnia and generalised anxiety disorder received Imovane 7.5 mg or nitrazepam 5 mg and the researchers compared the effects. They found the medications were both effective in improving the quality and duration of sleep among patients. However, Imovane was found to be more in improving anxiety levels. This may still vary from person to person due to individual responses.
Zopiclone is the active ingredient in Imovane so these medications are bioequivalent and identical. Zopiclone is a generic medication that is produced by companies other than the original innovator. Due to an expired patent, any pharmaceutical company can obtain the right to use the same chemical formula as Imovane to produce and sell zopiclone tablets. Imovane and zopiclone are identical in the following ways:
Stringent regulations manufacturing, packaging and testing sites to pass the same high-quality standards as those of branded medications. The price of zopiclone tablets is, however, 80-85% less than Imovane. The reason for this is that generic manufacturers are not required to repeat expensive clinical trials. Furthermore, they do not pay for expensive advertising and competition between generic manufacturers reduces the price even further.
Patients who are struggling with sleepless nights and looking for an effective solution can now simply order Imovane online. This medication is sourced from leading manufacturers so patients can be sure of high-quality products. The hassles of visiting a land-based pharmacy like traffic congestions, parking shortages, long queues and closed shops can all be avoided when buying this medication online. Other benefits of zopiclone include:
Customers can safely order sleeping tablets from the comfort of their own home, provided they have internet access. Payment methods are secure as SSL (Secure Sockets Layer) encryption software ensures safe transactions. Once a customer places an order, UK and EU packages are dispatched within 24 hours and arrive at the customer's selected destination within a few days.
Updated: 14th January 2021
Review Due: January 2022
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