Nitrazepam Dosage Instructions

Nitrazepam Dosage Instructions

From food, technology, appliances and everything in between, almost every product or service in this world is paired with instructions. Instructions are usually a set of rules or guidelines which are put into place to ensure safety and usefulness.

Medication is no exception as sleeping pills like nitrazepam come with a strict instruction list. Nitrazepam instructions are usually subdivided into two sections which are usage instructions and dosage guidelines. The beneficial effects of nitrazepam tablets can be extracted through instruction adherence.

Nitrazepam dosage instructions work on a simple principle called "start low, go slow". This method is often utilised with sleeping pills as it ensures that patients avoid dependence or tolerance. All patients are encouraged to start with the lowest effective dose at the beginning of their treatment plan.

Starting dosage:

  • Adults: The usual adult dose is 5 mg to 10 mg (1 to 2 tablets) at bedtime.
  • Elderly or debilitated patients: The recommended dose for patients in this category is 2.5 mg (half a tablet) to 5 mg (1 whole tablet) at bedtime.

Doses can be accordingly increased if necessary, however, patients must remember not to exceed the 10 mg maximum dosage mark in a 24-hour period.

Usage Instructions:

  • The tablet should be ingested with a full glass of water.
  • The pill can be taken with or without food - experts recommend that patients avoid high-fat meals as it can affect the tablets absorption rate.
  • Patients must never take a double dose to make up for missed doses. If a single dose is missed, patients are advised to take it as soon as possible if the time frame is appropriate. If it is already well within the night and a 6-to-8-hour sleep cycle is not possible, patients should skip the missed dose and continue with the next scheduled dose the following night.
  • If patients find themselves waking up during the night after taking their nitrazepam dosage, they are strongly advised not to consume another dose in hopes to fall asleep again as this can cause daytime drowsiness.

How Long Nitrazepam Diazepam Last?

According to the National Sleep Foundation guidelines, adults need between 7 to 9 hours of sleep per night. However, experts pin the ideal duration at 6 to 8 hours as too much sleep can also lead to fatigue and lethargy.

Patients with insomnia get less than half of these sleep durations if they are lucky. This causes a significant decline in their mental and physical capabilities. Thus, it is of utmost importance that patients seek a viable solution to treat the disorder.

One of the most popular sleep medications is nitrazepam. The effects produced by a single nitrazepam dosage can last 6 to 8 hours. Unlike other treatment options like diazepam, which last 4 to 6 hours, nitrazepam mimics standard sleep durations, making it the ideal treatment choice for patients who have trouble not only falling asleep, but staying asleep too.

Nitrazepam exerts stronger sedative effects than diazepam, thus, its effects last longer as well. A study comparing the durational effects and efficacy of the two benzodiazepines concluded that nitrazepam is a more efficient sleeping tablet. However, some patients prefer diazepam due to their individual needs, tolerance to the treatment and other specific factors that make it ideal for them.

How Long Does Nitrazepam Stay in Your System?

When experts analyse how long a particular medication lasts in the body, they focus on peak levels and half-lives. Peak level refers to the highest concentration of a substance in an individual's bloodstream while the half-life represents how long it takes for the body to eliminate half of a treatments dose.

Unlike other treatments in the benzodiazepine class, nitrazepam is a safer option due to its short-acting nature. Once absorbed into the bloodstream, nitrazepam acts within 30 to 60 minutes with peak concentration levels reached within 2 hours. The tablets half-life is averaged at 24 hours.

Since the tablets peak is reached so soon, the compound is more swiftly eliminated after the tablets durational effects have seized. The following are rough estimates of how long the compound stays in the system.

  • Urine: 1-2 days
  • Blood: 1-2 days

Although these figures may seem high, they are substantially lower than other sleeping tablets in the benzodiazepine class.

Other factors that might influence how long a nitrazepam dosage lasts in the body is:

  • Age - Younger patients who take the tablet, will experience standard elimination durations while older patients will experience longer ones. This is due to the different metabolic rates that patients in different age groups have.
  • Body Mass Index, or BMI - Nitrazepam is deposited into adipose (fat) tissues. Individuals who have a higher BMI will have a considerable amount of nitrazepam metabolites in the body. An offset BMI can also negatively affect liver functionality, which means that the compound will be eliminated at a slower rate.
  • Dosage amounts - Patients who consume higher doses of the tablet are more likely to have the compound lingering in their system for an extended period.
Take Nitrazepam Every Day

Can I Take Nitrazepam Every Day?

Most patients believe that nitrazepam cannot be used daily due to the potency of its effects, however, these assumptions are erroneous. In fact, many patients with insomnia require daily doses to rebalance their sleep schedule.

A single nitrazepam dosage can be consumed on consecutive days until the end of a treatment plan, which is typically 2-3 weeks. If doses are missed, the treatment plan is likely to go on for a few extra days. This is acceptable as long as the total number of days allocated to the treatment plan is not exceeded.

Before commencing with a treatment plan, patients are encouraged to consult with a medical professional and research online - to confirm the frequency and pattern they should follow when taking the tablet - as instructions can differ from patient to patient.

Nitrazepam Withdrawal Symptoms

Withdrawal symptoms are usually experienced when the tablet is not taken according to dosage, usage, frequency or duration instructions. There are several possible symptoms that can indicate withdrawal. However, the most common is usually a mix of physical and psychological aspects.

Common physical symptoms include:

  • Anxiety
  • Persistent and unpleasant memories
  • Short-term memory issues
  • Paranoia
  • Panic attacks

Common psychological symptoms include

  • Abdominal pains or a distended abdomen
  • Tinnitus
  • Sweating
  • Light and sound sensitivity
  • Severe headaches
  • Muscle spasms
  • Heart palpitations
  • Flu-like symptoms
  • Diarrhoea
  • Blurred vision

Patients can avoid experiencing withdrawal symptoms from nitrazepam 10 mg tablets by adhering to all guidelines and instructions accompanying the tablet.

Updated: 23rd January 2021
Review Due: January 2022



Fueled with a passion to try and help people less fortunate than himself Steve immersed himself in the medical industry. By researching new and innovative medical advancements and regularly sharing important information on social media Steve intends to make a difference where it matters most, people's health. His wealth of knowledge and keen eye for detail will help keep our readers informed and contribute towards improved health.

Harry Murphy – Mar 05, 2021
Dear Steve, superb article. Your keen eye for detail and empathy with your readers is reflected in your writing. The importance of following user instructions and dosage guidelines cannot be under estimated and your blog does an excellent job of highlighting this. Harry Murphy

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